Rituximab-CHOP Induced Interstitial Pneumonitis in Patients with Disseminated Extranodal Marginal Zone B Cell Lymphoma
Yonsei Medical Journal
; : 155-158, 2008.
Article
in En
| WPRIM
| ID: wpr-158187
Responsible library:
WPRO
ABSTRACT
A 69-year-old male was diagnosed in February 2004 with stage IV extranodal marginal zone B cell lymphoma involving the mediastinal nodes, lung parenchyma and bone marrow with high LDH. Shortness of breath developed following the 5th course of Rituximab-CHOP chemotherapy (cyclophosphamide, Vincristine, Doxorubicin, Prednisolone). Bronchoscopy guided transbronchial lung biopsy revealed interstitial thickening and type II pneumocyte activation, compatible with interstitial pneumonitis. After treatment with prednisolone a complete resolution of the dyspnea was observed. The patient was well on routine follow-up at the outpatient clinic, with no progression of lymphoma or interstitial pneumonitis.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Vincristine
/
Biopsy
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Prednisone
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Antineoplastic Combined Chemotherapy Protocols
/
Doxorubicin
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Tomography, X-Ray Computed
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Lung Diseases, Interstitial
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Lymphoma, B-Cell, Marginal Zone
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Cyclophosphamide
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Antibodies, Monoclonal
Limits:
Aged
/
Humans
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Male
Language:
En
Journal:
Yonsei Medical Journal
Year:
2008
Type:
Article