LINAC Radiosurgery for Cerebral Arteriovenous Malformation

ABSTRACT

OBJECTIVE: The author conducts a retrospective study to analyze long-term outcome and complication of LINAC radiosurgery for cerebral arteriovenous malformation(AVM). METHODS: We performed a detailed long-term follow-up study of 31 patients who could be followed up more than 2 years, with AVM treated by LINAC radiosurgery during January, 1996 to July, 2001. At the time of radiosurgery, the mean age was 47 years (range: 13-68). The median follow up period after radiosurgery was 27.2 months (range: 24-36). In all patients, AVM were completely covered with a 50~90% isodose line. The margin dose delivered by the LINAC was 14~28Gy(mean: 20.9Gy) at the periphery. RESULTS: Angiographic complete obliteration rate was 74.2% at 2 years after radiosurgery. Hemorrhage occured in 2cases(6.5%) at 12 and 14months after radiosurgery retrospectively, and 1patient died. Radiation related complication was developed in 1case(3.2%). CONCLUSION: LINAC radiosurgery is safe and effective in the treatment of cerebral arteriovenous malformation.