Vogt-Koyanagi-Harada disease occurring during pegylated interferon-alpha2b and ribavirin combination therapy for chronic hepatitis C / 대한간학회지
The Korean Journal of Hepatology
;
: 61-65, 2011.
Article
in English
| WPRIM
| ID: wpr-169273
ABSTRACT
Vogt-Koyanagi-Harada (VKH) disease is a multisystem syndrome characterized by ocular (uveitis and retinal detachment), neurological (headache, tinnitus, and meningitis), and integumentary (vitiligo, alopecia, and poliosis) involvement. Although the pathogenesis of VKH disease is not well understood, an autoimmune T-cell response to a melanocyte-associated antigen is considered to be a cause of VKH disease. The complex immunological response to interferon and ribavirin may induce or exacerbate the autoimmune condition; however, VKH disease is a very rare complication associated with interferon therapy in chronic hepatitis C. We report a case of VKH disease occurring during pegylated interferon-alpha2b and ribavirin combination therapy for chronic hepatitis C.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Antiviral Agents
/
Polyethylene Glycols
/
Ribavirin
/
Prednisolone
/
Magnetic Resonance Imaging
/
Fluorescein Angiography
/
Tomography, X-Ray Computed
/
Uveomeningoencephalitic Syndrome
/
Interferon-alpha
/
Hepatitis C, Chronic
Limits:
Female
/
Humans
Language:
English
Journal:
The Korean Journal of Hepatology
Year:
2011
Type:
Article
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