Encapsulating peritoneal sclerosis: case series from a university center
The Korean Journal of Internal Medicine
; : 587-593, 2013.
Article
in En
| WPRIM
| ID: wpr-175090
Responsible library:
WPRO
ABSTRACT
BACKGROUND/AIMS:
Encapsulating peritoneal sclerosis (EPS) is an often-fatal complication of long-term peritoneal dialysis (PD). We here report the clinical features of EPS in Korean PD patients from a single university center.METHODS:
The data were collected retrospectively from 606 PD patients at Kyungpook National University Hospital, between August 2001 and August 2011. The diagnosis of EPS was based on clinical signs and symptoms, and confirmed by radiological findings.RESULTS:
Eight patients (1.3%, four males) were diagnosed with EPS. The mean age of the patients was 48.5 years (range, 33 to 65). The mean duration of PD was 111.8 months (range, 23 to 186). All patients except for one had three or more episodes of peritonitis. Seven patients were diagnosed with EPS after stopping PD, and only one stayed on PD after initial diagnosis and treatment. Total parenteral nutrition and corticosteroids, in addition to tamoxifen therapy, were used to treat most of the patients, and one patient underwent surgery (adhesiolysis). The overall mortality rate was 50%.CONCLUSIONS:
EPS is a serious, life-threatening complication in patients on long-term PD. To reduce the incidence and mortality rate of EPS, careful monitoring and early diagnosis is needed.Key words
Full text:
1
Index:
WPRIM
Main subject:
Peritonitis
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Tamoxifen
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Time Factors
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Tomography, X-Ray Computed
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Retrospective Studies
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Peritoneal Dialysis
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Treatment Outcome
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Parenteral Nutrition, Total
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Adrenal Cortex Hormones
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Peritoneal Fibrosis
Type of study:
Observational_studies
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Screening_studies
Limits:
Adult
/
Aged
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Female
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Humans
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Male
Country/Region as subject:
Asia
Language:
En
Journal:
The Korean Journal of Internal Medicine
Year:
2013
Type:
Article