Detection of Ocular Toxoplasma gondii Infection in Chronic Irregular Recurrent Uveitis by PCR
The Korean Journal of Parasitology
;
: 229-231, 2012.
Article
in English
| WPRIM
| ID: wpr-175370
ABSTRACT
Toxoplasma gondii is a zoonotic parasite resulting in human infections and one of the infectious pathogens leading to uveitis and retinochoroiditis. The present study was performed to assess T. gondii infection in 20 ocular patients with chronic irregular recurrent uveitis (20 aqueous humor and 20 peripheral blood samples) using PCR. All samples were analyzed by nested PCR targeting a specific B1 gene of T. gondii. The PCR-positive rate was 25% (5/20), including 5% (1) in blood samples, 25% (5) in aqueous humor samples, and 5% (1) in both sample types. A molecular screening test for T. gondii infection in ocular patients with common clinical findings of an unclear retinal margin and an inflammatory membrane over the retina, as seen by fundus examination, may be helpful for early diagnosis and treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Aqueous Humor
/
Recurrence
/
Toxoplasma
/
Uveitis
/
Blood
/
Toxoplasmosis, Ocular
/
Polymerase Chain Reaction
/
Chronic Disease
Type of study:
Diagnostic study
/
Screening study
Limits:
Humans
Language:
English
Journal:
The Korean Journal of Parasitology
Year:
2012
Type:
Article
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