Differences in Clinical Characteristics between Patients with Non-Erosive Reflux Disease and Erosive Esophagitis in Korea
Journal of Korean Medical Science
; : 1318-1322, 2010.
Article
in En
| WPRIM
| ID: wpr-177036
Responsible library:
WPRO
ABSTRACT
Gastroesophageal reflux disease (GERD) is caused by abnormal reflux of gastric contents into the esophagus. GERD can be divided into two groups, erosive esophagitis and non-erosive reflux disease (NERD). The aim of this study was to compare the clinical characteristics of patients with erosive esophagitis to those with NERD. All participating patients underwent an upper endoscopy during a voluntary health check-up. The NERD group consisted of 500 subjects with classic GERD symptoms in the absence of esophageal mucosal injury during upper endoscopy. The erosive esophagitis group consisted of 292 subjects with superficial esophageal erosions with or without typical symptoms of GERD. Among GERD patients, male gender, high body mass index, high obesity degree, high waist-to-hip ratio, high triglycerides, alcohol intake, smoking and the presence of a hiatal hernia were positively related to the development of erosive esophagitis compared to NERD. In multivariated analysis, male gender, waist-to-hip ratio and the presence of a hiatal hernia were the significant risk factors of erosive esophagitis. We suggest that erosive esophagitis was more closely related to abdominal obesity.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Triglycerides
/
Alcohol Drinking
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Smoking
/
Esophagitis, Peptic
/
Gastroesophageal Reflux
/
Body Mass Index
/
Sex Factors
/
Risk Factors
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Gastroscopy
/
Waist-Hip Ratio
Type of study:
Etiology_studies
/
Risk_factors_studies
Limits:
Adult
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Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
En
Journal:
Journal of Korean Medical Science
Year:
2010
Type:
Article