A Case of Hydrogen Peroxide Proctitis / 대한소화기내시경학회지

ABSTRACT

Hydrogen peroxide is a safe and useful disinfectant that has achieved widespread utility in various clinical settings. However, hydrogen peroxide may cause mucosal damage and contact injury when applied to the surface of the gut wall. Endoscopically, hydrogen peroxide colitis and proctitis can mimic acute ulcerative colitis, ischemic colitis, or pseudomembranous colitis such as mucosal whitening, erythema, frothy bubbles, granularity and ulceration. We have experienced a case of hydrogen peroxide proctitis in a 37- year-old female patient. She visited our hospital due to symptoms such as hematochezia, anal pain and pelvic pain after insertion of 15 mL of 3% hydogen peroxide. Colonscopy revealed rectal mucosal whitening, severe erythema and scattered small ulcerations up to 12 cm from the anal verge. Pathologic finding revealed neutrophil infiltration in the lamina propria and intact colonic crypt. Herein we report a case of hydrogen peroxide proctitis with reviewed literatures.