Clinicopathologic Characteristics of Stage IV Early Gastric Cancer
Journal of the Korean Gastric Cancer Association
;
: 136-140, 2008.
Article
in Korean
| WPRIM
| ID: wpr-180125
ABSTRACT
PURPOSE:
Stage IV early gastric carcinoma (EGC) is a rare disease. We report here on 10 cases of EGC that showed metastasis in more than 15 lymph nodes. MATERIALS ANDMETHODS:
A total of 8354 cases of gastric carcinoma in patients who underwent surgical procedures between January 2001 and January 2007 at Samsung Medical Center were studied, and 10 cases were classified as stage IV EGC. We investigated their clinicopathologic characteristics.RESULTS:
There were 5 males and 5 females. Their ages at operation ranged from 46 to 76 years with a mean age of 61. All of the 10 patients had undergone curative resection for gastric cancer. The pathological diagnosis confirmed that all of the patients had tumor confined to the submucosa. The median size of the tumors was 5.3cm and the mean number of dissected nodes was 45.5 with a mean number of 22.2 involved nodes. Six cases were classified as the diffuse type and 4 were classified as the intestinal type by Lauren's classification. Histologically, 3 cases were signet ring cell carcinoma, 3 were poorly differentiated, 2 were moderately differentiated and 2 were well differentiated adenocarcinoma. Endolymphatic invasion was found in 9 cases. The median follow-up was 31 months. Adjuvant chemotherapy was done in 9 patients, and the patient who did not receive chemotherapy died by cerebrovascular accident. 2 patient had recurrence of gastric cancer and 7 survived without recurrence.CONCLUSION:
More cases should be collected and further studies on the molecular and cellular tumor characteristics are required to characterize these tumors that show aggressive lymphatic spread.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Stomach Neoplasms
/
Adenocarcinoma
/
Follow-Up Studies
/
Chemotherapy, Adjuvant
/
Carcinoma, Signet Ring Cell
/
Stroke
/
Rare Diseases
/
Gastrectomy
/
Lymph Nodes
Type of study:
Observational study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Language:
Korean
Journal:
Journal of the Korean Gastric Cancer Association
Year:
2008
Type:
Article
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