Long Term Effectiveness of Doxazosin in Men with Lower Urinary Tract Symptoms Suggesting of Benign Prostatic Hyperplasia / 대한비뇨기과학회지
Korean Journal of Urology
;
: 1003-1006, 2008.
Article
in Korean
| WPRIM
| ID: wpr-181861
ABSTRACT
PURPOSE:
The aim of this study was to evaluate the efficacy of doxazosin over 6 years in men with benign prostatic hyperplasia(BPH). MATERIALS ANDMETHODS:
This retrospective study enrolled 33 patients with symptomatic BPH who were prescribed an alpha-blocker from January 1999 to December 2000. We evaluated the changes of International Prostate Symptom Score(IPSS), maximal flow rate(Qmax), quality of life(QoL) and residual urine volume(RUV) between before and after 6-year of treatment.RESULTS:
The percentages of improvement were 40.2% in total IPSS, 40.6% in obstructive symptom, 39.4% in irritative symptom, 44.7% in QoL, 124.8% in Qmax, 33.5% in RUV(p<0.05). Three patients(9.1%) experienced acute urinary retention and BPH-related surgery was performed in 6 patients (18.2%).CONCLUSIONS:
Our study revealed that long-term treatment over 6 years with alpha-blocker resulted in significant improvements in the IPSS, QoL, Qmax and RUV.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Observational study
Limits:
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Urology
Year:
2008
Type:
Article
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