Quinupristin/Dalfopristin-induced Sweet's Syndrome
The Korean Journal of Internal Medicine
; : 187-190, 2003.
Article
in En
| WPRIM
| ID: wpr-181876
Responsible library:
WPRO
ABSTRACT
Quinupristin/Dalfopristin is a new combination of streptogramin antibiotics designed specifically to treat clinically significant infections due to Vancomycin-resistant Enterococcus Faecium. Sweet's syndrome is characterized by painful skin plaques, which is associated with dermal neutrophilic infiltration, fever and peripheral blood leukocytosis. Drug-induced Sweet's syndrome has a temporal relationship between drug ingestion, clinical presentation and the temporally-related resolution of lesions following drug withdrawal or on treatment with systemic corticosteroids. A 63-year-old woman received Quinupristin/Dalfopristin for acute pyelonephritis developed fever, arthralgia, vomiting, and painful erythematous skin plaques. A skin biopsy showed neutrophilic dermatosis, and there was rapid resolution of the symptoms and cutaneous lesions after discontinuation of Quinupristin/Dalfopristin, consistent with drug-induced Sweet's syndrome. To date, there has been no reported case of Sweet's syndrome associated with the use of Quinupristin/Dalfopristin.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Skin
/
Virginiamycin
/
Sweet Syndrome
/
Anti-Bacterial Agents
Limits:
Female
/
Humans
Language:
En
Journal:
The Korean Journal of Internal Medicine
Year:
2003
Type:
Article