Delayed Hemolytic Transfusion Reaction with Alloimmunization of Rh Phenotype: A Two-Case Study / 대한수혈학회지
Korean Journal of Blood Transfusion
; : 163-169, 2017.
Article
in Ko
| WPRIM
| ID: wpr-18195
Responsible library:
WPRO
ABSTRACT
Delayed hemolytic transfusion reaction is difficult to prevent using an unexpected antibody test performed prior to transfusion, and unlike acute hemolytic transfusion reaction, it occurs a few days after blood transfusion. Hence, determining the reason for delayed hemolytic transfusion reaction may be a tim-consuming task for clinicians Here, we report our experience of two cases of delayed hemolytic transfusion reaction as a result of the unexpected antibody production to Rh blood group antigens after transfusion. The first patient with a history of transfusion during admission was identified as having anti-E and anti-C antibodies according to the antibody identification test at the time of re-admission. The second patient who had chronic blood transfusion due to cancer treatment was found to have anti-C antibody. Both patients received transfusion of Rh antigen-compatible RBC units only after unexpected antibody development. However, like both cases, patients receiving continuous blood transfusion should be considered for a routine Rh phenotype test.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Phenotype
/
Blood Group Antigens
/
Blood Transfusion
/
Transfusion Reaction
/
Antibodies
/
Antibody Formation
Type of study:
Prognostic_studies
Limits:
Humans
Language:
Ko
Journal:
Korean Journal of Blood Transfusion
Year:
2017
Type:
Article