A Case of Combined Hepatocellular-Cholangiocarcinoma with Sarcomatous Transformation and Second Primary Colon Cancer / 대한간학회지
The Korean Journal of Hepatology
; : 142-147, 2004.
Article
in Ko
| WPRIM
| ID: wpr-183422
Responsible library:
WPRO
ABSTRACT
Combined hepatocellular-cholangiocarcinoma is a rare form of primary liver cancer, featuring both hepatocellular and biliary epithelial differentiations. An intrahepatic tumor may be considered as a metastatic lesion. It has been suggested in the literature that the likelihood of metastasis in the cirrhotic liver is lower than that in the non-cirrhotic liver. A rare case of combined hepatocellular-cholangiocarcinoma and second primary colon adenocarcinoma in a 67-year-old male patient with liver cirrhosis is presented. Histologically, the intrahepatic mass was composed of a spindle cell sarcomatous component; a hepatocellular carcinoma component; and a cholangiocarcinoma component. There were focal transitional regions among the different components. Immunohistochemically, the cholangiocarcinoma component of the intrahepatic mass showed positive reactions for CK-7 but negative reactions for CK-20. The adenocarcinoma of the colon showed positive reactions for CK-20 but negative reactions for CK-7.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Bile Duct Neoplasms
/
Bile Ducts, Intrahepatic
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English Abstract
/
Adenocarcinoma
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Neoplasms, Second Primary
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Colonic Neoplasms
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Cholangiocarcinoma
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Carcinoma, Hepatocellular
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Liver Neoplasms
Limits:
Aged
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Humans
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Male
Language:
Ko
Journal:
The Korean Journal of Hepatology
Year:
2004
Type:
Article