Anaphylaxis after Thiopental and Rocuronium Induction: A case report / 대한마취과학회지

ABSTRACT

Anaphylaxis and anaphylactoid reactions that occur during anesthesia may range from minor systemic effects to life-threatening or fatal effects. A 88-yr-old man was scheduled for laparoscopic nephrectomy. He had no history of allergy and had never previously undergone general anesthesia, though several spinal anesthesias were performed for TUR-B using 0.5% heavy bupivacaine. General anesthesia was induced with alfentanil 0.5 mg, thiopental 250 mg, and rocuronium bromide 50 mg. After thiopental injection, the man became irritable, and after rocuronium injection ventilation became difficult and tachycardia appeared; blood pressure could not be checked. The operation was canceled and a skin prick test was performed. Seven weeks later, he underwent uneventful anesthesia with etomidate and vecuronium.