Live birth in a woman with recurrent implantation failure and adenomyosis following transfer of refrozen-warmed embryos / 대한생식의학회지
Clinical and Experimental Reproductive Medicine
; : 181-184, 2016.
Article
in En
| WPRIM
| ID: wpr-188149
Responsible library:
WPRO
ABSTRACT
The aim was to report a healthy live birth using re-vitrified-warmed cleavage-stage embryos derived from supernumerary warmed embryos after frozen embryo transfer (ET) in a patient with recurrent implantation failure (RIF). The case was a 39-year-old female with a history of polycystic ovarian syndrome and adenomyosis, along with RIF. After ovarian hyperstimulation, 33 cumulus-oocyte complexes were retrieved and fertilized with conventional in vitro fertilization and intracytoplasmic sperm injection. Because of the risk of ovarian hyperstimulation syndrome, 16 grade B and C embryos were vitrified. After 3 and 6 months, 3 and 4 B–C warmed embryos were transferred to the uterus, respectively. However, implantation did not take place. Ten months later, four embryos were warmed, two grade B 8-cell embryos were transferred, and two embryos were re-vitrified. One year later, the two re-vitrified cleavage-stage embryos were warmed, which resulted in a successful live birth. This finding showed that following first warming, it is feasible to refreeze supernumerary warmed embryos for subsequent ET in patients with a history of RIF.
Key words
Full text:
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Index:
WPRIM
Main subject:
Polycystic Ovary Syndrome
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Uterus
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Fertilization in Vitro
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Ovarian Hyperstimulation Syndrome
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Sperm Injections, Intracytoplasmic
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Embryo Transfer
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Embryonic Structures
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Live Birth
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Vitrification
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Adenomyosis
Limits:
Adult
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Female
/
Humans
Language:
En
Journal:
Clinical and Experimental Reproductive Medicine
Year:
2016
Type:
Article