Relationship between Intussusception and Vitamin C Concentrations of Whole Blood and Plasma / 대한소아소화기영양학회지
Korean Journal of Pediatric Gastroenterology and Nutrition
; : 167-174, 2001.
Article
in Ko
| WPRIM
| ID: wpr-191714
Responsible library:
WPRO
ABSTRACT
PURPOSE: Adenovirus infection with swollen Peyer patches in the ileum, known as one of the causes of intussusception, may cause vitamin C depletion in human body because vitamin C is a first line antioxidant. Or low vitamin C status in human body makes the man more susceptible to infection of adenovirus in the ileum with a markedly swollen lymph node. In this study, we tried to find out the relationship between pediatric intussusceptions and vitamin C concentrations of whole blood and plasma. METHODS: Whole blood and plasma vitamin C concentrations of fifty-seven patients with intussusceptions from May 1995 to December 1998 at the Gyeongsang National University Hospital were compared with those of 256 normal healthy children. Vitamin C was measured by the 2,4-dinitrophenylhydrazine methods. RESULTS: The average age of patients (male=39, female=18) with intussusceptions was fifteen months of age. Whole blood vitamin C concentrations of patients and healthy children were 1.49+/-0.64 mg/dL, and 2.18+/-0.49 mg/dL, respectively. Plasma vitamin C concentrations of patients and healthy children were 0.59+/-0.36 mg/dL, 1.47+/-0.56 mg/dL, respectively. But no differences in the vitamin C concentrations of whole blood and plasma according to age, degree of leukocytosis, fever, interval from onset, hematochezia, and need for operation were found. CONCLUSION: Whole blood and plasma vitamin C concentrations of patients with intussusceptions were lower than those of healthy children (P=0.0001). Prospective studies are needed to elucidate whether these results were consequences or causes of intussusceptions.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Peyer's Patches
/
Plasma
/
Ascorbic Acid
/
Vitamins
/
Adenoviridae
/
Adenoviridae Infections
/
Human Body
/
Fever
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Gastrointestinal Hemorrhage
/
Ileum
Type of study:
Observational_studies
Limits:
Child
/
Humans
Language:
Ko
Journal:
Korean Journal of Pediatric Gastroenterology and Nutrition
Year:
2001
Type:
Article