Invasive Pulmonary Aspergillosis after Influenza A Infection in an Immunocompetent Patient / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
; : 260-263, 2013.
Article
in En
| WPRIM
| ID: wpr-194717
Responsible library:
WPRO
ABSTRACT
Invasive aspergillosis has emerged as a major cause of life-threatening infections in immunocompromised patients. Recently, patients with chronic obstructive pulmonary disease, who have been receiving corticosteroids for a long period, and immunocompetent patients in the intensive care unit have been identified as nontraditional hosts at risk for invasive aspergillosis. Here, we report a case of invasive pulmonary aspergillosis after influenza in an immunocompetent patient. The patient's symptoms were nonspecific, and the patient was unresponsive to treatments for pulmonary bacterial infection. Bronchoscopy revealed mucosa hyperemia, and wide, raised and cream-colored plaques throughout the trachea and both the main bronchi. Histologic examination revealed aspergillosis. The patient recovered quickly when treated systemically with voriconazole, although the reported mortality rates for aspergillosis are extremely high. This study showed that invasive aspergillosis should be considered in immunocompetent patients who are unresponsive to antibiotic treatments; further, early extensive use of all available diagnostic tools, especially bronchoscopy, is mandatory.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Influenza A virus
/
Aspergillosis
/
Bacterial Infections
/
Trachea
/
Bronchi
/
Bronchoscopy
/
Mortality
/
Immunocompromised Host
/
Adrenal Cortex Hormones
/
Pulmonary Disease, Chronic Obstructive
Type of study:
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Tuberculosis and Respiratory Diseases
Year:
2013
Type:
Article