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Primary Gastrointestinal Lymphoma: A Comparison of Survival Rates between Gastric and Intestinal Non-Hodgkin's Lymphoma / 대한암학회지
Article in Ko | WPRIM | ID: wpr-195531
Responsible library: WPRO
ABSTRACT
PURPOSE: The purpose of this study was to evaluate the differences in survival rates between primary gastric and intestinal gastrointestinal non-Hodgkin's lymphoma (NHL) and to investigate risk factors for survival. MATERIALS AND METHODS: We reviewed survival rates and risk factors in 60 cases with stage I and II primary gastrointestinal lymphomas treated at Keimyung University Hospital between January 1972 and August 1999. RESULTS: No differences in sex, age, histology, stage, or percentage of curative resection were observed between primary gastric and intestinal lymphoma. The overall 10-year survival rates of gastric and intestinal NHL were 68.1% and 39.6%, respectively (p<0.05). The overall 10-year survival rates in stage I gastric and intestinal NHL were 66.7% and 70.0%, respectively, while those in stageII were 65.1% and 23.7%, respectively (p<0.001). A multivariate analysis of risk factors for survival revealed that the site of origin (5.68, CI=1.8-17.5) and stage (4.22, CI= 1.19-14.85) were significantly correlated with prognosis (p<0.05). There was no significant difference in the expression of bcl-2 and p53 between gastric and intestinal NHL. Furthermore bcl-2 and p53 expressions were not correlated with the prognosis. CONCLUSION: This study indicates that stage II primary intestinal lymphoma has lower survival rate than gastric lymphoma.
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Full text: 1 Index: WPRIM Main subject: Prognosis / Lymphoma, Non-Hodgkin / Multivariate Analysis / Survival Rate / Risk Factors / Lymphoma Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Language: Ko Journal: Journal of the Korean Cancer Association Year: 2001 Type: Article
Full text: 1 Index: WPRIM Main subject: Prognosis / Lymphoma, Non-Hodgkin / Multivariate Analysis / Survival Rate / Risk Factors / Lymphoma Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Language: Ko Journal: Journal of the Korean Cancer Association Year: 2001 Type: Article