A Localized Cutaneous Paecilomyces lilacinus Infection Treated with Voriconazole / 대한피부과학회지

ABSTRACT

Paecilomyces is a hyaline hyphomycete that exists worldwide. Paecilomyces lilacinus is associated most frequently with human infection. A 72-year-old male presented with a 1-month history of pruritic erythematous scaly plaque on his left shoulder. Tissue specimen from his cutaneous lesion showed granulomatous inflammation in the dermis and revealed fungal hyphae and spores within giant cells. The pathogen was identified as Paecilomyces lilacinus through fungus culture. Oral itraconazole was begun, but there was no improvement after 14 weeks. The lesions improved after treatment with oral voriconazole. We suggest that voriconazole as a promising useful therapeutic option in Paecilomyces lilacinus infection.