Improvement of Dementia Screening Accuracy of Mini-Mental State Examination by Education-Adjustment and Supplementation of Frontal Assessment Battery Performance
Journal of Korean Medical Science
; : 1522-1528, 2013.
Article
in En
| WPRIM
| ID: wpr-212594
Responsible library:
WPRO
ABSTRACT
This study aimed to investigate whether the demographic variable-adjustment and supplementation of Frontal Assessment Battery (FAB) score can improve the screening ability of Mini-Mental State Examination (MMSE) for dementia and its subtypes. Five hundred forty-one non-demented comparison (NC) and 474 dementia (320 Alzheimer's disease [AD]; 139 non-Alzheimer's disease dementia [NAD]; and 15 mixed AD-NAD dementia) individuals living in the community were included. Education-adjusted MMSE (MMSE-edu) score showed significantly better screening accuracy for overall dementia, AD, and NAD than MMSE raw score. FAB-supplemented MMSE (MMSE-FAB) score had significantly better screening ability for NAD, but not for overall dementia and AD, than MMSE raw score alone. Additional supplementation of FAB to MMSE-edu further increased the ability for overall dementia or NAD screening, but not for AD screening. Further education adjustment of MMSE-FAB also improved its ability for overall dementia, AD, and NAD screening. These results strongly support the usefulness of education-adjustment and supplementation of frontal function assessment to improve screening performance of MMSE for dementia and its subtypes, NAD in particular.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Demography
/
ROC Curve
/
Area Under Curve
/
Dementia
/
Diagnosis, Differential
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Alzheimer Disease
/
Neuropsychological Tests
Type of study:
Diagnostic_studies
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Prognostic_studies
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Screening_studies
Limits:
Aged
/
Aged80
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Female
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Humans
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Male
Language:
En
Journal:
Journal of Korean Medical Science
Year:
2013
Type:
Article