Incidence and Clinical Course of Left Ventricular Systolic Dysfunction in Patients with Carbon Monoxide Poisoning
Korean Circulation Journal
;
: 665-671, 2016.
Article
in English
| WPRIM
| ID: wpr-217213
ABSTRACT
BACKGROUND AND OBJECTIVES:
Carbon monoxide (CO) poisoning can cause tissue hypoxia and left ventricular systolic dysfunction (LVSD) requiring intensive medical management. Our objectives were to find incidence and clinical course of LVSD CO intoxicated patients and make a clinical scoring to predict LVSD. SUBJECTS ANDMETHODS:
We included all consecutive patients with CO exposure in the emergency room. LVSD was defined by LVEF 100/min), pulmonary edema on chest X-ray, serum NT pro-BNP (>100 pg/mL), troponin-I (>0.1 ng/mL) and lactic acid (>4.0 mg/dL) after a univariate analysis. Combining these into a clinical score, according to their beta score after a multivariate analysis (rage=0-16), allowed prediction of LVSD with a sensitivity of 84% and specificity of 91% (reference ≥8, area under the curve=0.952, p<0.001)CONCLUSION:
About 31% showed LVSD in patients with CO poisoning, and most of them (86%, 18 of 21 patients) recovered within 3 days. Patients with a higher clinical score (≥8) might have LVSD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Poisoning
/
Pulmonary Edema
/
Thorax
/
Carbon
/
Carbon Monoxide
/
Carbon Monoxide Poisoning
/
Echocardiography
/
Incidence
/
Multivariate Analysis
/
Cohort Studies
Type of study:
Diagnostic study
/
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
/
Male
Language:
English
Journal:
Korean Circulation Journal
Year:
2016
Type:
Article
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