Four months of magnetized water supplementation improves glycemic control, antioxidant status, and cellualr DNA damage in db/db mice / 한국영양학회지
Journal of Nutrition and Health
; : 401-410, 2016.
Article
in Ko
| WPRIM
| ID: wpr-217759
Responsible library:
WPRO
ABSTRACT
PURPOSE:
Water is magnetically charged upon contact with a magnet. Although magnetic water products have been promoted since the 1930's, they have not received wide acceptance since their effectiveness is still in question; however, some have reported their therapeutic effects on the body, especially the digestive, nervous, and urinary systems.METHODS:
In this study, the effect of magnetized water on glycemic control of 14 diabetic mice (CB57BK/KsJ-db/db) in comparison with 10 control mice (CB57BK/KsJ-db/+(db/+)) was investigated. Seven diabetic control (DMC) mice and seven diabetic mice + magnetized water (DM+MW) were kept for 16 weeks, followed by intraperitoneal glucose tolerance test (IPGTT). Weekly blood glucose was measured from tail veins. Blood obtained from heart puncture was used for HbA1c analysis.RESULTS:
Blood glucose level showed a significant difference starting from the 10th week of study (496.1 ± 10.2 mg/dl in DMC vs. 437.9 ± 76.9 mg/dl in DM+MW). Blood glucose followed by IPGTT showed no significant difference between groups at 0, 30, 60, 90, and 120 min, although glucose level at 180 min was significantly reduced in DM+MW mice. Plasma insulin level in DM+MW groups was only 39.5% of that of DMC groups (5.97 ± 1.69 ng/ml in DMC vs. 2.36 ± 0.94 ng/ml in DM+MW). Levels of HbA1c were 12.4% and 9.7% in DMC and DM+MW groups, respectively.CONCLUSION:
These results show the promising therapeutic effect of magnetized water in regulating blood glucose homeostasis; however, long-term supplementation or mechanistic study is necessary.Key words
Full text:
1
Index:
WPRIM
Main subject:
Plasma
/
Tail
/
Veins
/
Blood Glucose
/
DNA Damage
/
DNA
/
Water
/
Punctures
/
Therapeutic Uses
/
Glucose
Limits:
Animals
Language:
Ko
Journal:
Journal of Nutrition and Health
Year:
2016
Type:
Article