Congenital Melanocytic Nevus Showing an Unusual Clinical Manifestation / 대한피부과학회지
Korean Journal of Dermatology
;
: 648-651, 2011.
Article
in Korean
| WPRIM
| ID: wpr-222354
ABSTRACT
Completely neurotized melanocytic nevi are often clinically and histologically indistinguishable from neurofibromas. We report a 23-year-old female who presented with a dark brown plaque with an underlying soft blue subcutaneous nodule in the left infra-axillary area. The skin biopsy revealed markedly increased melanocytic proliferation and nests of nevus cells within dermo-epidermal junction and upper dermis. Circumscribed, non-encapsulated tumor of the dermis was composed of loosely-spaced spindle cells and wavy stroma. Spindle cells in the lower dermis showed staining for S-100, but failed to express glial fibrillary acidic protein and Leu-7. We present an interesting case because the lesion presented as a soft blue subcutaneous nodule suggested an underlying hemangioma or neurofibroma initially, but was shown to be a neurotized melanocytic nevus based on immunohistochemical examination.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Skin
/
Biopsy
/
Dermis
/
Glial Fibrillary Acidic Protein
/
Hemangioma
/
Neurofibroma
/
Nevus
/
Nevus, Pigmented
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2011
Type:
Article
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