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The usage of Mayo staging system in Chinese patients with primary light chain amyloidosis / 中华血液学杂志
Chinese Journal of Hematology ; (12): 278-282, 2016.
Article in Zh | WPRIM | ID: wpr-234003
Responsible library: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the usage of Mayo staging system in Chinese patients with primary light chain (LC) amyloidosis.</p><p><b>METHOD</b>Clinical data, treatment and outcome of 162 primary LC amyloidosis patients with Mayo Clinic staging in Peking Union Medical College Hospital from January 2009 to June 2015 were retrospectively analyzed.</p><p><b>RESULTS</b>The median age of 162 patients with Mayo Clinic 2004 stage was 57 (20-81) y, of them 62.3% were male. The number of patients with stage I to III were 44 (27.2%), 69 (42.6%), and 49 (30.2%), respectively. The median overall survival was not reached, 23 months and 12 months in patients with Mayo Clinic 2004 stage I, II, and III, respectively (P<0.001). Among 128 patients with Mayo Clinic 2012 stage, 48 patients (37.5%), 32 patients (25.0%), 32 patients (25.0%) and 16 patients (12.5%) were staged as Mayo Clinic 2012 stage 1 to 4, and the median OS was not reached, not reached, 13 months and 3 months, respectively (P<0.001).</p><p><b>CONCLUSION</b>Mayo Clinic staging systems had important prognostic value in patients with primary LC amyloidosis.</p>
Subject(s)
Full text: 1 Index: WPRIM Main subject: Prognosis / Retrospective Studies / Diagnosis / Immunoglobulin Light-chain Amyloidosis / Amyloidosis Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male Language: Zh Journal: Chinese Journal of Hematology Year: 2016 Type: Article
Full text: 1 Index: WPRIM Main subject: Prognosis / Retrospective Studies / Diagnosis / Immunoglobulin Light-chain Amyloidosis / Amyloidosis Type of study: Diagnostic_studies / Observational_studies / Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male Language: Zh Journal: Chinese Journal of Hematology Year: 2016 Type: Article