Clinical study on toxicity-attenuation effect of Yiguan Decoction in treatment of non-small cell lung cancer with NP protocol of chemotherapy / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 396-399, 2007.
Article
in Zh
| WPRIM
| ID: wpr-234760
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To observe the toxicity-attenuation effect of Yiguan Decoction (YGD) in treatment of non-small cell lung cancer (NSCLC) with NP protocol of chemotherapy.</p><p><b>METHODS</b>Ninety-two NSCLC patients were randomly assigned to two groups equally, the control group given only NP protocol of chemotherapy and the treated group given the same protocol of chemotherapy plus YGD. Hepatic function, T-cell subgroup and NK cell were examined, and quality of life (QOL) was evaluated with scoring by Karnofsky performance status (KPS), Quality of Life Questionnaire-Core30 (EORTC QLQ-C30) and Special Scale for lung cancer (EORTC LC13) issued by European Organization for Research and Treatment of Cancer.</p><p><b>RESULTS</b>The effects on all the above-mentioned indexes in the treated group were better than those in the control group after 42 days of treatment (P <0.05).</p><p><b>CONCLUSION</b>YGD could not only reduce the side and toxic effects caused by NP protocol of chemotherapy in NSCLC patients but also improve their QOL.</p>
Full text:
1
Index:
WPRIM
Main subject:
Quality of Life
/
Drugs, Chinese Herbal
/
Antineoplastic Combined Chemotherapy Protocols
/
Cisplatin
/
Treatment Outcome
/
Carcinoma, Non-Small-Cell Lung
/
Therapeutic Uses
/
Drug Therapy
/
Drug Therapy, Combination
/
Lung Neoplasms
Type of study:
Guideline
Limits:
Aged
/
Female
/
Humans
/
Male
Language:
Zh
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2007
Type:
Article