A meningomyelocele with normal intracranial signs on ultrasound and false-negative amniotic fluid alpha-fetoprotein and acetylcholinesterase
Obstetrics & Gynecology Science
; : 223-227, 2014.
Article
in En
| WPRIM
| ID: wpr-24458
Responsible library:
WPRO
ABSTRACT
Neural tube defects are the major targets of prenatal diagnoses, along with Down syndrome. Prenatal diagnosis of spina bifida is possible at second trimester of gestation through alpha-fetoprotein and acetylcholinesterase biochemistry assays and ultrasound. In particular, the discovery of characteristic intracranial signs on ultrasound leads to a very high diagnosis rate. However, it is rare for spina bifida to present without intracranial signs while also showing normal values of maternal serum alpha-fetoprotein, amniotic fluid alpha-fetoprotein, and acetylcholinesterase. In our hospital, a fetus with spina bifida was delivered at 37+5 weeks' gestation by cesarean section, and was continually followed up over 2 years to date.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Pregnancy Trimester, Second
/
Prenatal Diagnosis
/
Acetylcholinesterase
/
Reference Values
/
Biochemistry
/
Alpha-Fetoproteins
/
Cesarean Section
/
Spinal Dysraphism
/
Ultrasonography
/
Meningomyelocele
Type of study:
Diagnostic_studies
Limits:
Female
/
Humans
/
Pregnancy
Language:
En
Journal:
Obstetrics & Gynecology Science
Year:
2014
Type:
Article