Studies on release behavior of sustained release tablets of extracts of Gardenia by antioxidant activity / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 3274-3277, 2014.
Article
in Zh
| WPRIM
| ID: wpr-244582
Responsible library:
WPRO
ABSTRACT
Using sustained release tablets of gardenia extract as model drug and DPPH radical scavenging capacity as antioxidant index, the feasibility of using pharmacodynamics index was explored to evaluate sustained release tablets. Applying the established quantifiable method of DPPH radical scavenging to the dissolved liquid of model drug, release profiles and biological effects profiles were drawn, and their correlation was discussed. A good correlation was observed by linear regression and f2 actor, suggesting that the indicator could be used to evaluate sustained release tabletsofextracts of gardenia in which iridoids were mainly involved.
Full text:
1
Index:
WPRIM
Main subject:
Oxidation-Reduction
/
Pharmacology
/
Picrates
/
Tablets
/
Biphenyl Compounds
/
Pharmacokinetics
/
Plant Extracts
/
Kinetics
/
Linear Models
/
Chemistry
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2014
Type:
Article