The value of MR dynamic time-resolved subtracted imaging in evaluating the blood supply by systemic artery in patients with lung cancer / 中国肺癌杂志
Chinese Journal of Lung Cancer
; (12): 13-17, 2003.
Article
in Zh
| WPRIM
| ID: wpr-252390
Responsible library:
WPRO
ABSTRACT
<p><b>BACKGROUND</b>To explore the application value of MR dynamic time-resolved subtracted imaging in qualitative and quantitative assessment of blood supply by systemic artery in patients with lung cancer.</p><p><b>METHODS</b>A prospective study using MR FSPGR pulse sequence dynamic scan after contrast enhancement was undertaken in fifty-one patients with lung cancer which were proved by cytology or/and histology. The time-resolved subtracted imaging were acquired using the pre- and post-enhanced images in different phases of pulmonary circulation during the first-pass period (FPP) of contrast agent. The time-signal curves of FPP at four ROI placed on pulmonary artery (PA), descending aorta (DA), mass (M) and contralateral pulmonary parenchyma (PP), and the ST (start-time) and PT (peak-time) of those four ROI were measured. The enhancement ratio of the signals of M/PP at PA/DA peak time (E MP , E MA , E PP , E PA ) were calculated.</p><p><b>RESULTS</b>According to the time-resolved subtracted imaging during PA phase, intensity of the signal was low in 7 cases, medium in 2, but not enhanced in other 42 cases. All the 51 cancer masses were remarkably enhanced during DA phase. During FPP, the ST [(5.90±0.51)s] and PT [(12.75±0.67)s] of PP were slightly later than the ST [(4.19±0.43)s] and PT [(10.59±0.66)s] of PA, while the ST [(11.03±0.80)s] and PT [(33.62±3.06)s] of cancer masses were later than ST [(9.43±0.59)s] and PT [(19.81±4.14)s] of DA. E MA was significantly higher than E MP (91.47%±18.83% vs 15.38%±11.03%, P < 0.001), while E PP were remarkably higher than E PA (273.83%±48.60% vs 140.65%±24.40%, P < 0.001).</p><p><b>CONCLUSIONS</b>MR dynamic time-resolved subtracted imaging is feasible to be a non-invasive technique in qualitative and relatively quantitative assessment of blood supply by systemic artery in patients with lung cancer.</p>
Full text:
1
Index:
WPRIM
Type of study:
Observational_studies
/
Qualitative_research
Language:
Zh
Journal:
Chinese Journal of Lung Cancer
Year:
2003
Type:
Article