Factors affecting the prognosis and selection of local excision for low rectal cancer / 中华肿瘤杂志
Chinese Journal of Oncology
; (12): 141-143, 2007.
Article
in Zh
| WPRIM
| ID: wpr-255702
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the factors affecting the result and selection of local excision for low rectal cancer.</p><p><b>METHODS</b>The clinical data of 101 patients with low rectal cancer treated by local excision were retrospectively analyzed. Survival was estimated using the Kaplan-Meier. The factors influencing on the survival were analyzed using univariate (Log rank) and multivariate (Cox model) analysis methods.</p><p><b>RESULTS</b>Of 101 patients in this series, 91 patients underwent transanal excision, 9 had transsacral excision, 1 recieved transvaginal excision. Postopertative complication developed in 6 patients (5.9%). No death occurred within 30 postoperative days. Five T4 patients underwent preoperative radiotherapy, and 34 received postoperative radiotherapy. The overall 5-year survival rate was 91.0% for the whole group, and it was 100%, 92.6%, 77.1%, 83.3% for patients with Tis, T1, T2, and T3/T4 lesion, respectively. The incidence of local recurrence was 15. 8%. Univariate analysis revealed that pathological T stage, tumor size (> 3 cm), lymphovascular invasion, ulcerative lesion, adjuvant radiotherapy and local recurrence were significant factors affecting the survival (P <0.05). However, by multivariate analysis, only tumor size ( > 3 cm) and local recurrence were found to be the significant prognostic predictors.</p><p><b>CONCLUSION</b>The important selection criteria for local excision in the treatment of low rectal cancer may include T1 stage, well or moderate differentiation,tumor size < or = 3 cm, no lymphovascular invasion.</p>
Full text:
1
Index:
WPRIM
Main subject:
Pathology
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Prognosis
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Radiation Effects
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Radiotherapy
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Rectal Neoplasms
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Rectum
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General Surgery
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Multivariate Analysis
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Retrospective Studies
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Follow-Up Studies
Type of study:
Observational_studies
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Prognostic_studies
Limits:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
Language:
Zh
Journal:
Chinese Journal of Oncology
Year:
2007
Type:
Article