Effect of qilong capsule on hemoreology in acute stress blood stasis rats / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 362-365, 2004.
Article
in Chinese
| WPRIM
| ID: wpr-256352
ABSTRACT
<p><b>OBJECTIVE</b>To study the influence of Qilong capsule (QLC) on the hemoreology in acute stress blood stasis model rats.</p><p><b>METHOD</b>The model of acute stress blood stasis rats were induced by putting the rats into ice-water between hyodermic epinephrine twice of 1 mg x kg(-1). With the models, the effect of QLC on hemoreology such as whole blood viscosity, whole blood reduction viscosity, plasma viscosity, haematocrit (Hct), erythrocyte deformation and erythrocyte aggregation were observed.</p><p><b>RESULT</b>QLC 0.6, 0.3, 0.15 g x kg(-1) could significantly reduce the increase of whole blood viscosity at high-middle-low shear rate, reduce the whole blood reduction viscosity at middle-low shear rate, reduce Hct and erythrocyte aggregation, and increase the erythrocyte deformation in acute stress blood stasis rats (P < 0.05, P < 0.01, compared with vehicle). QLC 0.6, 0.3 g x kg(-1) could also reduce plasma viscosity (P < 0.05, P < 0.01, compared with vehicle).</p><p><b>CONCLUSION</b>QLC can significantly improve some indexes of hemoreology in acute stress blood stasis rats.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oligochaeta
/
Pharmacology
/
Plants, Medicinal
/
Stress, Physiological
/
Blood Viscosity
/
Capsules
/
Drugs, Chinese Herbal
/
Materia Medica
/
Chemistry
/
Rats, Wistar
Limits:
Animals
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2004
Type:
Article
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