A comparison of postoperative emergence agitation between sevoflurane and thiopental anesthesia induction in pediatric patients / 대한마취과학회지
Korean Journal of Anesthesiology
; : 373-378, 2015.
Article
in En
| WPRIM
| ID: wpr-25868
Responsible library:
WPRO
ABSTRACT
BACKGROUND:
This study was performed to compare the incidence of emergence agitation (EA) between inhalation and intravenous anesthesia induction in children after sevoflurane anesthesia.METHODS:
In this prospective and double-blind study, 100 children aged 3 to 7 years were enrolled. Subjects were randomly assigned to the sevoflurane (Group S) or thiopental (Group T) anesthesia induction groups. Anesthesia was induced using 8% sevoflurane and 4-6 mg/kg thiopental in Groups S and T, respectively. Anesthesia was maintained with nitrous oxide and sevoflurane. The children were evaluated at 5 and 20 min after arrival in the postanesthesia care unit (PACU) with a four-point agitation scale and the Pediatric Anesthesia Emergence Delirium scale. The incidence of EA and administration of the rescue agent were recorded.RESULTS:
The incidence of EA was significantly lower in Group T compared to Group S at 5 min after PACU arrival (3/49 patients, 6% vs. 12/47 patients, 26%, P = 0.019). However, there was no difference between the two groups at 20 min after PACU arrival (23/49 vs. 19/47 patients in Group T vs. Group S, P = 0.425). The overall incidence of EA was 60% (28/47 patients) in Group S and 41% (20/49 patients) in Group T (P = 0.102). The number of children who received propofol as a rescue agent was significantly lower in Group T (Group S 14/47 vs. Group T 5/49, P = 0.031).CONCLUSIONS:
Intravenous anesthesia induction with thiopental reduced the incidence of EA in the early PACU period compared to inhalation induction with sevoflurane in 3- to 7-year-old children undergoing sevoflurane anesthesia.Key words
Full text:
1
Index:
WPRIM
Main subject:
Pediatrics
/
Thiopental
/
Propofol
/
Inhalation
/
Double-Blind Method
/
Incidence
/
Prospective Studies
/
Delirium
/
Dihydroergotamine
/
Anesthesia
Type of study:
Clinical_trials
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
Limits:
Child
/
Humans
Language:
En
Journal:
Korean Journal of Anesthesiology
Year:
2015
Type:
Article