Experimental study on ectopic prefabrication of vascularized mandible graft with autogenous ribs / 中华口腔医学杂志
Chinese Journal of Stomatology
;
(12): 544-546, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-260239
ABSTRACT
<p><b>OBJECTIVE</b>To explore a method for ectopic prefabrication of mandible with vascular pedicle.</p><p><b>METHODS</b>Cancellous bone blocks harvested from the dog ribs were packaged with mandible-shaped titanium mesh scaffold and implanted into latissimus dorsi of dog with thoracodorsal artery and vein through the scaffold. After 12 weeks, bone formation and vascularization were evaluated by gross inspection, histological examination and immunohistochemistry.</p><p><b>RESULTS</b>Vascularized mandible with thoracodorsal artery and vein were formed and histological staining and immunohistochemisty confirmed new bone formation and vascularization.</p><p><b>CONCLUSIONS</b>There is feasibility for ectopic prefabrication of vascularized mandible graft using cancellous ribs, which provides a new method for mandibular defect reconstruction. Experimental study on ectopic prefabrication of vascularized mandible graft with autogenous ribs.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Osteogenesis
/
Ribs
/
General Surgery
/
Transplantation, Autologous
/
Bone Transplantation
/
Plastic Surgery Procedures
/
Tissue Engineering
/
Mandible
/
Methods
Limits:
Animals
Language:
Chinese
Journal:
Chinese Journal of Stomatology
Year:
2012
Type:
Article
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