Analysis of chemical constituents of anti-myocardial ischemia fraction of Corydalis yanhusuo / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1717-1719, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-264832
ABSTRACT
<p><b>OBJECTIVE</b>To establish the HPLC fingerprint of anti-myocardial ischemia fraction of Corydalis yanhusuo, and to investigate its chemical constituents by LC-MS-MS.</p><p><b>METHOD</b>The separation was performed at 30 degrees C on a Dikma Diamonsil C18 column (4.6 mm x 250 mm, 5 microm) by isocratic elution with acetonitrile-water (2377) (containing 0.8% acetic acid and 0.2% triethylamine) as the mobile phase at a flow rate of 1.0 mL x min(-1), with UV detection at 335 nm.</p><p><b>RESULT</b>A satisfactory fingerprint was obtained by HPLC method, 12 common peaks were selected as the fingerprint peaks, and 8 among them were identified according to the chromatographic behavior and mass spectroscopic data by comparison with those of authentic standard.</p><p><b>CONCLUSION</b>This method is simple, sensitive and reliable, can be used to investigate the chemical constituents of anti-myocardial ischemia fraction of C. yanhusuo and control the quality.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Drugs, Chinese Herbal
/
Chemistry
/
Chromatography, High Pressure Liquid
/
Corydalis
/
Tandem Mass Spectrometry
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2008
Type:
Article
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