Influence of Shenfu Injection on the quality of life of lung cancer patients receiving chemotherapy / 南方医科大学学报
Journal of Southern Medical University
; (12): 2090-2092, 2011.
Article
in Zh
| WPRIM
| ID: wpr-265710
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the influence of Shenfu Injection (SHF) on the quality of life of patients with advanced non-small cell lung cancer (NSCLC) receiving chemotherapy.</p><p><b>METHODS</b>A total of 133 patients with NSCLC receiving at least two cycles of chemotherapy with taxol plus cisplatin (TP)/vinorelbine plus cisplatin (NP) or gemcitabine plus cisplatin (GP) were randomized into SHF pre-treatment group (with SHF given only in the first cycle) and SHF post-treatment group (with SHF given only in the second cycle). The Quality of Life Questionnaire-Core 30 (QLQ-C30) and the Functional Living Index-Cancer (FLIC) were used to evaluate the quality of life of the patients after the treatments.</p><p><b>RESULTS</b>Both of the groups showed improved quality of life after the treatments (P<0.01), but the improvements were more obvious in SHF pre-treatment group (P<0.05). SHF showed favorable effects in relieving such adverse effects as fatigue, nausea, vomiting and diarrhea associated with the chemotherapy.</p><p><b>CONCLUSION</b>SHF can improve the quality of life in NSCLC patients receiving chemotherapies.</p>
Full text:
1
Index:
WPRIM
Main subject:
Quality of Life
/
Vinblastine
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Vomiting
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Drugs, Chinese Herbal
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Antineoplastic Combined Chemotherapy Protocols
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Surveys and Questionnaires
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Cisplatin
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Paclitaxel
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Carcinoma, Non-Small-Cell Lung
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Therapeutic Uses
Type of study:
Clinical_trials
Limits:
Adult
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Aged
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Female
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Humans
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Male
Language:
Zh
Journal:
Journal of Southern Medical University
Year:
2011
Type:
Article