A Case of Sub-acute Bacterial Endocarditis associated with a Positive ANCA Serology / 대한신장학회지
Korean Journal of Nephrology
;
: 476-480, 2008.
Article
in Korean
| WPRIM
| ID: wpr-26994
ABSTRACT
Antineutrophil cytoplasmic antibodies (ANCA) directed against either proteinase-3 or myeloperoxidase are associated with a limited group of small vessel vasculitic syndromes. C-ANCA is regarded as highly specific for idiopathic ANCA-associated vasculitis (AAV). However, C-ANCA is not specific for Wegeners granulomatosis and has been reported in the course of a variety of infectious conditions. Sub-acute bacterial endocarditis is a notable concern because it may be associated with C-ANCA. The misdiagnosis of bacterial endocarditis as AAV and the administration of immunosuppressive treatment could aggravate the infection. We describe a patient with sub-acute bacterial endocarditis who presented with features mimicking vasculitis and positive C-ANCA by indirect immunofluorescence and for anti-PR3 antibodies by antigen-specific ELISA.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Vasculitis
/
Peroxidase
/
Fluorescent Antibody Technique, Indirect
/
Antibodies, Antineutrophil Cytoplasmic
/
Cytoplasm
/
Diagnostic Errors
/
Endocarditis, Bacterial
/
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
/
Glycosaminoglycans
/
Antibodies
Type of study:
Diagnostic study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Nephrology
Year:
2008
Type:
Article
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