Application of 1% lauromacrogol in the treatment of facial refractory hemangioma and vascular malformations / 中华整形外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the clinical effect of 1% lauromacrogol for the treatment of facial refractory hemangioma and vascular malformation.</p><p><b>METHODS</b>From Sept 2009 to Nov 2011, 55 patients (20 male, 35 female, 1 month to 30 years) with different types of facial hemangiorwa and vascular malformation about 1.0 cm x (0. 5-5.0) cm x 10.0 cm in size, underwent 1% lauromacrogol intratumor injection therapy. Generally, the injection dose, concentration, frequency were determined by the age of the patients, the volume and depth of the lesion. The dose was limited to 10 mg every time. The injection interval is 14 weeks.</p><p><b>RESULTS</b>After followed up for 3-16 months, 41 cases were cured, 9 cases were greatly improved, and 5 were partially improved. Skin necrosis happened in only 2 cases.</p><p><b>CONCLUSIONS</b>Lauromacrogol is safe, simple and effective as a sderosing agent for the treatment of facial refractory hemangioma and vascular malformation. It provides a new and alternative way for the treatment of facial refractory hemangioma and vascular malformation.</p>