Advance in flavonoids biosynthetic pathway and synthetic biology / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 4124-4128, 2016.
Article
in Zh
| WPRIM
| ID: wpr-272723
Responsible library:
WPRO
ABSTRACT
Flavonoids are the valuable components in medicinal plants, which possess a variety of pharmacological activities, including anti-tumor, antioxidant and anti-inflammatory activities. There is an unambiguous understanding about flavonoids biosynthetic pathway, that is,2S-flavanones including naringenin and pinocembrin are the skeleton of other flavonoids and they can transform to other flavonoids through branched metabolic pathway. Elucidation of the flavonoids biosynthetic pathway lays a solid foundation for their synthetic biology. A few flavonoids have been produced in Escherichia coli or yeast with synthetic biological technologies, such as naringenin, pinocembrin and fisetin. Synthetic biology will provide a new way to get valuable flavonoids and promote the research and development of flavonoid drugs and health products, making flavonoids play more important roles in human diet and health.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2016
Type:
Article