Time interval from the end of sperm processing to artificial intrauterine in semination with husband's sperm correlates to the rate of clinical pregnancy / 中华男科学杂志
National Journal of Andrology
; (12): 532-535, 2015.
Article
in Zh
| WPRIM
| ID: wpr-276063
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the influence of the time interval from the end of semen processing to artificial intrauterine in semination with husband's sperm (AIH-IUI) on the rate of clinical pregnancy.</p><p><b>METHODS</b>This study involved 191 AIH-IUI cycles with the same ovulation induction protocol. After Percoll density gradient centrifugation, we divided the sperm into four groups based on the incubation time 0-19, 20-39, 40-59, and 60-80 min, and again into another four groups according to the total progressively motile sperm count (TPMC) (0-9), (10-20), (21-30), and > 30 x 10(6). We analyzed the correlation of the clinical pregnancy rate with the time interval from the end of sperm processing to AIH-IUI and with other influencing factors, such as maternal age, infertility duration, and semen quality.</p><p><b>RESULTS</b>The rate of clinical pregnancy was significantly higher in the 20-39 min group (18.3%) than in the 0-19, 40-59, and 60-80 min groups (12.7, 11.4 and 9.1%) (all P < 0.05). The (10-20) x 10(6) group achieved a remarkably higher pregnancy rate (16.7%) than the (0-9), (21-30), and > 30 x 10(6) groups (0, 11.4, and 8.3%) (all P < 0.05). Logistic multivariate analysis showed that the rate of clinical pregnancy was decreased with the increased age of the women (OR 0.89, 95% CI 0.83-0.94) but significantly elevated in the 20-39 min group (OR 2.11, 95% CI 1.34-3.13) and of (10-20) x 10(6) group (OR 2.06, 95% CI 1.32-3.46).</p><p><b>CONCLUSION</b>The time interval from the end of sperm processing to AIH-IUI is a most significant factor influencing the rate of clinical pregnancy of AIH-IUI.</p>
Full text:
1
Index:
WPRIM
Main subject:
Semen
/
Sperm Count
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Spermatozoa
/
Therapeutics
/
Time Factors
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Centrifugation, Density Gradient
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Pregnancy Rate
/
Semen Analysis
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Infertility
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Insemination, Artificial, Homologous
Type of study:
Guideline
Limits:
Female
/
Humans
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Male
/
Pregnancy
Language:
Zh
Journal:
National Journal of Andrology
Year:
2015
Type:
Article