Advances in the study of inhibitors of kinases and nuclear factors for treating allergic asthma / 药学学报
Acta Pharmaceutica Sinica
; (12): 689-695, 2012.
Article
in Zh
| WPRIM
| ID: wpr-276257
Responsible library:
WPRO
ABSTRACT
Currently, about 300 million people worldwide are affected by asthma. Most of these sufferers inhale immunosuppressants (ie corticosteroids) and beta-adrenergic receptor agonists for their asthma treatment. However, about 5%-10% of patients of asthma have poor response to such treatment. Investigation of kinase signaling pathway and nuclear transcription factor as a target molecule in the treatment of allergic asthma has been the concern of scholars home and abroad. This paper reviewed inhibitors of kinase signaling pathway and nuclear transcription factors for the treatment of asthma.
Full text:
1
Index:
WPRIM
Main subject:
Asthma
/
Transcription Factors
/
Protein-Tyrosine Kinases
/
Signal Transduction
/
Mitogen-Activated Protein Kinases
/
Therapeutic Uses
/
Protein Kinase Inhibitors
/
Drug Therapy
/
Phosphatidylinositol 3-Kinase
/
Metabolism
Limits:
Animals
/
Humans
Language:
Zh
Journal:
Acta Pharmaceutica Sinica
Year:
2012
Type:
Article