Phenolic glucosides from the leaves of Pieris japonica / 药学学报
Acta Pharmaceutica Sinica
; (12): 284-290, 2008.
Article
in En
| WPRIM
| ID: wpr-277861
Responsible library:
WPRO
ABSTRACT
The aim of the study is to investigate chemical constituents of the leaves of Pieris japonica. The isolation and purification of the constituents were performed by various chromatography and spectral analysis. Three new phenolic glucosides, erythro-syringoylglycerol 4-O-beta-D-glucoside (1), 1-(2-beta-D-glucopyranoxyl-4-methoxyl-6-hydroxyphenyl)-3-hydroxyl-l-propanone (3), erythro-l-(4-hydroxyl-3-methoxyphenyl)-2-[4-(3-beta-D-glucopyranoxypropyl)-2 ,6-dimethoxyphenoxy]-1, 3-propanediol (4), along with five known phenolic glucosides, syringoylglycerol 8-O-beta-D-glucoside (2), magnolenin C (5), syringaresinol mono-beta-D-glucoside (6), 3-(4-hydroxyl-3-methyphenyl)-1 -propanol-l-O-beta-D-glucoside (7) and 3, 5-dimethoxyl-4-hydroxybenzyl alcohol 4-O-beta-D-glucoside (8) were isolated and identified from the plant leaves. Compounds 1 and 2 inhibited significantly (P <0.01) the proliferation of murine T and B cells at concentration of 1 x 10(-6) mol L(-1), in vitro.
Full text:
1
Index:
WPRIM
Main subject:
Phenols
/
Plants, Medicinal
/
Chemistry
/
Lignans
/
Plant Leaves
/
Ericaceae
/
Glucosides
/
Immunosuppressive Agents
Language:
En
Journal:
Acta Pharmaceutica Sinica
Year:
2008
Type:
Article