Genetic polymorphism of 9 STR loci in Han nation population in Shandong Province / 中国医学科学院学报
Zhongguo yi xue ke xue yuan xue bao
; Zhongguo yi xue ke xue yuan xue bao;(6): 620-625, 2002.
Article
in Zh
| WPRIM
| ID: wpr-278125
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study genetic polymorphism of 9 STR loci in Han nation population in Shangdong Province.</p><p><b>METHODS</b>We investigated 100 unrelated individuals of Han nation population in Shandong Province and studied their genetic distribution of 9 STR loci and Amelogenin locus. Primers of 10 loci were labeled with the NHS-ester fluorescent dye 5-FAM (blue), Joe (green) or NED (yellow). The data of Han nation population were generated by multiple amplification and subjected to GeneScan, genotype and genetic distribution analysis.</p><p><b>RESULTS</b>83 alleles and 220 genotypes were observed, with the corresponding frequency of 0.0050-0.4050 and 0.0100-0.2100. The average of heterozygosity was 0.7778, the accumulated discrimination power was 0.9999. The accumulated probability of exclusion paternity was 0.9999. The polymorphism information content was 0.5823-0.8396.</p><p><b>CONCLUSIONS</b>Chi-Square test indicated that the distribution of genotypes agreed with Hardy-Weinberg equilibrium.</p>
Full text:
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Index:
WPRIM
Main subject:
Polymorphism, Genetic
/
Repetitive Sequences, Nucleic Acid
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Genetic Markers
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China
/
Tandem Repeat Sequences
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Alleles
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Ethnology
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Gene Frequency
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Genetics
/
Genotype
Limits:
Humans
Country/Region as subject:
Asia
Language:
Zh
Journal:
Zhongguo yi xue ke xue yuan xue bao
Year:
2002
Type:
Article