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Genetic polymorphism of 9 STR loci in Han nation population in Shandong Province / 中国医学科学院学报
Zhongguo yi xue ke xue yuan xue bao ; Zhongguo yi xue ke xue yuan xue bao;(6): 620-625, 2002.
Article in Zh | WPRIM | ID: wpr-278125
Responsible library: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study genetic polymorphism of 9 STR loci in Han nation population in Shangdong Province.</p><p><b>METHODS</b>We investigated 100 unrelated individuals of Han nation population in Shandong Province and studied their genetic distribution of 9 STR loci and Amelogenin locus. Primers of 10 loci were labeled with the NHS-ester fluorescent dye 5-FAM (blue), Joe (green) or NED (yellow). The data of Han nation population were generated by multiple amplification and subjected to GeneScan, genotype and genetic distribution analysis.</p><p><b>RESULTS</b>83 alleles and 220 genotypes were observed, with the corresponding frequency of 0.0050-0.4050 and 0.0100-0.2100. The average of heterozygosity was 0.7778, the accumulated discrimination power was 0.9999. The accumulated probability of exclusion paternity was 0.9999. The polymorphism information content was 0.5823-0.8396.</p><p><b>CONCLUSIONS</b>Chi-Square test indicated that the distribution of genotypes agreed with Hardy-Weinberg equilibrium.</p>
Subject(s)
Full text: 1 Index: WPRIM Main subject: Polymorphism, Genetic / Repetitive Sequences, Nucleic Acid / Genetic Markers / China / Tandem Repeat Sequences / Alleles / Ethnology / Gene Frequency / Genetics / Genotype Limits: Humans Country/Region as subject: Asia Language: Zh Journal: Zhongguo yi xue ke xue yuan xue bao Year: 2002 Type: Article
Full text: 1 Index: WPRIM Main subject: Polymorphism, Genetic / Repetitive Sequences, Nucleic Acid / Genetic Markers / China / Tandem Repeat Sequences / Alleles / Ethnology / Gene Frequency / Genetics / Genotype Limits: Humans Country/Region as subject: Asia Language: Zh Journal: Zhongguo yi xue ke xue yuan xue bao Year: 2002 Type: Article