RNA interference (RNAi) as novel approach for gene silencing--review / 中国实验血液学杂志
Journal of Experimental Hematology
; (6): 1141-1144, 2005.
Article
in Zh
| WPRIM
| ID: wpr-280749
Responsible library:
WPRO
ABSTRACT
RNA interference (RNAi), a highly conserved evolutionary process of post-transcriptional gene silencing, can be triggered by small interfering RNAs (siRNAs) that mediate sequence-specific mRNA degradation. The article summarized some aspects of the mechanism of RNAi, siRNA design and delivery of siRNAs to mammalian somatic cells. And some hurdles in practice were also discussed.
Full text:
1
Index:
WPRIM
Main subject:
Transfection
/
RNA, Small Interfering
/
RNA Interference
/
Genetics
Limits:
Animals
/
Humans
Language:
Zh
Journal:
Journal of Experimental Hematology
Year:
2005
Type:
Article