Expression of nuclear factor-kappaB in traumatic cataract / 中华创伤杂志(英文版)
Chinese Journal of Traumatology
;
(6): 86-90, 2006.
Article
in English
| WPRIM
| ID: wpr-280931
ABSTRACT
<p><b>OBJECTIVE</b>To study the differences in expression of nuclear factor-kappaB (NF-kappaB) between human traumatic cataract and normal lenticular epithelial cells.</p><p><b>METHODS</b>Total RNA of anterior capsule specimens was taken under the microscope from normal cadaveric eyes donors and those suffering from traumatic cataract to make semi-quantitative RT-PCR and conduct analysis of differences in expression of NF-kappaB between them.</p><p><b>RESULTS</b>As compared with the mean of 0.8337 in normal control group, the expression equivalent of NF-kappaB was 0.9074 for the lenticular epithelial cells in traumatic cataract sufferers, and the differences are of noticeable significance (t = 2.447, P<0.05) accordingly.</p><p><b>CONCLUSIONS</b>NF-kappaB is likely a kind of transcription factor necessary to maintain metabolism of normal lenticular epithelial cells. Higher NF-kappaB available in the traumatic cataract sufferer's lenticular epithelial cells means NF-kappaB is of possible relevance to occurrence and development of traumatic cataract.</p>
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Therapeutics
/
Wounds and Injuries
/
Cataract
/
Polymerase Chain Reaction
/
NF-kappa B
/
Epithelial Cells
/
Genetics
/
Lens, Crystalline
/
Metabolism
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Chinese Journal of Traumatology
Year:
2006
Type:
Article
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