Interdigitating dendritic cell sarcoma/tumor: a clinicopathologic study / 中华病理学杂志
Chinese Journal of Pathology
; (12): 99-102, 2014.
Article
in Zh
| WPRIM
| ID: wpr-288157
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the clinicopathologic characteristics and diagnostic criteria of interdigitating dendritic cell sarcoma/tumor (IDCS/T).</p><p><b>METHODS</b>The clinical features, histologic findings and results of immunohistochemical study in six cases of IDCS/T were analyzed, with review of literature.</p><p><b>RESULTS</b>The age of patients ranged from 20 to 68 years. The sites of involvement included lymph node, tonsil and soft tissue. Histologically, the tumor cells were arranged in sheets, fascicles or whorls and intimately admixed with abundant lymphocytes and plasma cells. They were oval to spindly in shape and contained pale eosinophilic cytoplasm, oval nuclei and distinct nucleoli.Immunohistochemical study showed that the tumor cells were positive for S-100 protein and CD68.</p><p><b>CONCLUSIONS</b>IDCS/T is a rare malignant tumor with poor prognosis. It carries distinctive histologic pattern and immunophenotype. The entity needs to be distinguished from follicular dendritic cell sarcoma/tumor, anaplastic large cell lymphoma and other spindle cell sarcomas in occurring soft tissue.</p>
Full text:
1
Index:
WPRIM
Main subject:
Pathology
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Sarcoma
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Soft Tissue Neoplasms
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Thigh
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Vimentin
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Antigens, Differentiation, Myelomonocytic
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S100 Proteins
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Tonsillar Neoplasms
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Antigens, CD
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Histiocytosis, Langerhans-Cell
Type of study:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
Limits:
Adult
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Aged
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Female
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Humans
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Male
Language:
Zh
Journal:
Chinese Journal of Pathology
Year:
2014
Type:
Article