Study of DNA damage of buccal mucosal cells after wearing casting alloy crowns / 华西口腔医学杂志
West China Journal of Stomatology
; (6): 21-25, 2006.
Article
in Zh
| WPRIM
| ID: wpr-289016
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To test the corrosion behavior of three kinds of dental casting alloys and to investigate the effect of the released metal ions on the DNA damage of dog buccal mucosal cells.</p><p><b>METHODS</b>Three kinds of frequently used dental casting alloys were used to make full crowns for dogs. The concentration of the released metal ions was measured after the restoration of 2 weeks, 1 month, 2 months and 3 months. The DNA damage of buccal mucosal cells was studied by the method of SCGE.</p><p><b>RESULTS</b>The metal ions released from NiCr and NiCrBe were detected in buccal mucosal cells while the amount of the ions released from noble alloy (gold 58%) was too small to be detected. The DNA damage of mucosal cells increased after restoration of NiCr and NiCrBe crowns.</p><p><b>CONCLUSION</b>The noble alloy (gold 58%) is most corrosion resistant of the three alloys and has good biocompatibility. The NiCr and NiCrBe are prone to corrode and have cytotoxicity to cells.</p>
Full text:
1
Index:
WPRIM
Main subject:
DNA Damage
/
Corrosion
/
Crowns
/
Dental Alloys
/
Alloys
/
Gold
/
Ions
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Mouth Mucosa
Limits:
Animals
Language:
Zh
Journal:
West China Journal of Stomatology
Year:
2006
Type:
Article