Necessity of defunctioning stoma in low anterior resection for rectal cancer: a meta-analysis / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
; (12): 346-352, 2012.
Article
in Zh
| WPRIM
| ID: wpr-290788
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the necessity of defunctioning stoma in low anterior resection for rectal cancer below peritoneal reflection.</p><p><b>METHODS</b>The databases of Medline, Embase, Cochrane Library, Wanfang and CNKI were searched. The eligible studies were identified for pooled analyses.</p><p><b>RESULTS</b>Six randomized controlled trials with 648 cases(332 patients with defunctioning stoma and 316 without stoma) and 25 retrospective controlled trials with 10,722 cases(4,470 patients with defunctioning stoma and 6,252 without stoma) were included. Combined analyses showed that defunctioning stoma was effective for decreasing risk of postoperative anastomotic leakage (RR=0.33 and 95% CI0.21-0.53 for RCTs, OR=0.60 and 95% CI0.42-0.85 for retrospective studies), reoperation (RR=0.30, 95% CI0.16-0.53 for RCTs, OR=0.26 and 95% CI0.21-0.32 for retrospective studies) and mortality(OR=0.41, 95% CI0.27-0.62 for retrospective studies).</p><p><b>CONCLUSION</b>Defunctioning stoma should be routinely performed in low anterior resection for high-risk patients.</p>
Full text:
1
Index:
WPRIM
Main subject:
Postoperative Complications
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Rectal Neoplasms
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General Surgery
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Enterostomy
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Randomized Controlled Trials as Topic
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Anastomotic Leak
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Methods
Type of study:
Clinical_trials
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Observational_studies
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Systematic_reviews
Limits:
Humans
Language:
Zh
Journal:
Chinese Journal of Gastrointestinal Surgery
Year:
2012
Type:
Article