In vitro bactericidal activity of Jinghua Weikang Capsule and its individual herb Chenopodium ambrosioides L. against antibiotic-resistant Helicobacter pylori / 中国结合医学杂志
Chinese journal of integrative medicine
; (12): 54-57, 2013.
Article
in En
| WPRIM
| ID: wpr-293309
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the bactericidal effects of Jinghua Weikang Capsule and its major component Chenopodium ambrosioides L. on antibiotic-resistant Helicobacter pylori.</p><p><b>METHODS</b>Four clinical antibiotic-resistant H. pylori strains were isolated and incubated in liquid medium containing Jinghua Weikang Capsule or Chenopodium ambrosioides L. By means of time-kill curve method, the average colony counts and bactericidal rate were calculated at time points of 0, 4, 8 and 24 h after the incubation and the time-kill curves were charted.</p><p><b>RESULTS</b>Both Jinghua Weikang Capsule and Chenopodium ambrosioides L. at a concentration of 0.64 g/L showed obvious bactericidal effect against antibiotic-resistant H. pylori after 4 h of incubation.</p><p><b>CONCLUSION</b>Jinghua Weikang Capsule and Chenopodium ambrosioides L. are considered to be active against antibiotic-resistant H. pylori in vitro.</p>
Full text:
1
Index:
WPRIM
Main subject:
Pharmacology
/
In Vitro Techniques
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Drug Resistance, Microbial
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Drugs, Chinese Herbal
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Microbial Sensitivity Tests
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Helicobacter pylori
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Helicobacter Infections
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Sensitivity and Specificity
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Chenopodium ambrosioides
/
Plant Preparations
Type of study:
Diagnostic_studies
Limits:
Humans
Language:
En
Journal:
Chinese journal of integrative medicine
Year:
2013
Type:
Article