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In vitro bactericidal activity of Jinghua Weikang Capsule and its individual herb Chenopodium ambrosioides L. against antibiotic-resistant Helicobacter pylori / 中国结合医学杂志
Article in En | WPRIM | ID: wpr-293309
Responsible library: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the bactericidal effects of Jinghua Weikang Capsule and its major component Chenopodium ambrosioides L. on antibiotic-resistant Helicobacter pylori.</p><p><b>METHODS</b>Four clinical antibiotic-resistant H. pylori strains were isolated and incubated in liquid medium containing Jinghua Weikang Capsule or Chenopodium ambrosioides L. By means of time-kill curve method, the average colony counts and bactericidal rate were calculated at time points of 0, 4, 8 and 24 h after the incubation and the time-kill curves were charted.</p><p><b>RESULTS</b>Both Jinghua Weikang Capsule and Chenopodium ambrosioides L. at a concentration of 0.64 g/L showed obvious bactericidal effect against antibiotic-resistant H. pylori after 4 h of incubation.</p><p><b>CONCLUSION</b>Jinghua Weikang Capsule and Chenopodium ambrosioides L. are considered to be active against antibiotic-resistant H. pylori in vitro.</p>
Subject(s)
Full text: 1 Index: WPRIM Main subject: Pharmacology / In Vitro Techniques / Drug Resistance, Microbial / Drugs, Chinese Herbal / Microbial Sensitivity Tests / Helicobacter pylori / Helicobacter Infections / Sensitivity and Specificity / Chenopodium ambrosioides / Plant Preparations Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Chinese journal of integrative medicine Year: 2013 Type: Article
Full text: 1 Index: WPRIM Main subject: Pharmacology / In Vitro Techniques / Drug Resistance, Microbial / Drugs, Chinese Herbal / Microbial Sensitivity Tests / Helicobacter pylori / Helicobacter Infections / Sensitivity and Specificity / Chenopodium ambrosioides / Plant Preparations Type of study: Diagnostic_studies Limits: Humans Language: En Journal: Chinese journal of integrative medicine Year: 2013 Type: Article