Relationship between antibacterial activity of aloe and its anthaquinone compounds / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1034-1037, 2003.
Article
in Zh
| WPRIM
| ID: wpr-293735
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relationship between the antibacterial activity of aloe and its contents of anthaquinone compounds, measure and compale antibacterial activities of aloin and aloe-emodin, and analyse the effect of glycoside on the antibacterial activity of aloin.</p><p><b>METHOD</b>The antibacterial activities of the extracts from the outer leaf of Aloe saponaria Haw, aloin and aloe-emodin against three Gram-negative and two Gram-positive bacteria were investigated with the method of agar diffusion. The antibacterial effect of aloin on E. coli was further studied with scanning electron microscopy.</p><p><b>RESULT</b>The antibacterial activities of aloe showed to be dependent on the dose of anthraquinone, aloin (1 g x L(-1)) exhibited higher antibacterial activity [inhibition diameter > (7. 1 +/- 0.15) mm] than Aloe-emodin (inhibition diameter < 5.0 mm), and aloin changed the morphology of E. coli and damaged the outer cell structrue.</p><p><b>CONCLUSION</b>Anthraquinone compounds are the active antibacterial components in aloe and aloin is the main active compound. The glycoside makes it easy for aloin to invade cells and enhances its activity.</p>
Full text:
1
Index:
WPRIM
Main subject:
Pharmacology
/
Plants, Medicinal
/
Proteus vulgaris
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Pseudomonas aeruginosa
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Staphylococcus aureus
/
Bacillus subtilis
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Drugs, Chinese Herbal
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Chemistry
/
Anthraquinones
/
Emodin
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2003
Type:
Article