Study on preparation of testosterone undecanoate ethosomes and its in vitro transdermal penetration / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1371-1374, 2013.
Article
in Zh
| WPRIM
| ID: wpr-294107
Responsible library:
WPRO
ABSTRACT
Ethosomes, as a new vector for transdermal drug delivery, could obviously improve the transdermal penetration of drugs. In this study, we prepared testosterone undecanoate ethosomes, with TU ethosomes as the basic remedy, to determine its appearance, particle size, entrapment efficiency (EE) and membrane fluidity. Meanwhile, a transdermal test was conducted in mice, in order to determine the permeability characteristics of ethosomes as a vector for transdermal drug delivery, and compare transdermal behaviors of TU ethosomes, liposomes and their ethanol solutions.
Full text:
1
Index:
WPRIM
Main subject:
Skin Absorption
/
Testosterone
/
Administration, Cutaneous
/
Chemistry
/
Drug Delivery Systems
/
Liposomes
Limits:
Animals
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2013
Type:
Article