Chemical constituents in roots of Osbeckia opipara / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 414-418, 2009.
Article
in En
| WPRIM
| ID: wpr-298389
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the chemical constituents of the roots of Osbeckia opipara.</p><p><b>METHOD</b>Repeated column chromatography over silica gel, RP-18 and Sephadex LH-20, and preparative thin layer chromatography(PTLC) were used to isolate the compounds, whose structures were determined by spectroscopic methods by direct comparing spectral data with those reported references.</p><p><b>RESULT</b>From the MeOH extract of the roots O. opipara, twelve compounds were isolated and identified as follows lasiodiplodin (1) , de-O-methyllasiodiplodin (2), 2, 3- dihydro-2-hydroxy-2, 4-dimethyl-5-trans-propenylfuran-3-one (3), integracin (4), 5alpha, 8alpha-epidioxy-(22E, 24R)-ergosta-6, 22-dien-3beta-ol (5), 3, 3', 4'-tri-O-methylellagic acid (6), 5-hydroxymethyl furaldehyde (7), vomifolio (8) , betulintic acid (9), 2alpha-hydroxyursolic acid (10), (24R)-stigmast-4-ene-3-one (11), and eugenitin (12).</p><p><b>CONCLUSION</b>Compounds 1-12 were isolated from O. opipara for the first time.</p>
Full text:
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Index:
WPRIM
Main subject:
Spectrum Analysis
/
Triterpenes
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Plant Extracts
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Molecular Structure
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Chemistry
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Cholestenones
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Plant Roots
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Melastomataceae
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Fruiting Bodies, Fungal
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Fermentation
Language:
En
Journal:
China Journal of Chinese Materia Medica
Year:
2009
Type:
Article