The clinical evaluation of patients with pituitary adenomas undergone transsphenoidal microsurgery / 中华外科杂志
Chinese Journal of Surgery
; (12): 610-613, 2003.
Article
in Zh
| WPRIM
| ID: wpr-299976
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the overall effect of transsphenoidal microsurgery for pituitary adenomas in recent 5 years and to discuss the surgical technique, application of new technology and postoperative follow-up results.</p><p><b>METHODS</b>The clinical presentation, image characteristics, endocrinal findings, pathological types, tumor removal percentage, postoperative complication and follow-up of 1 462 patients with pituitary adenomas who underwent the transsphenoidal microsurgery from 1997 to 2002 were analysed retrospectively.</p><p><b>RESULTS</b>Total rate of tumor removal for the patients achieved 97.0% in the patients with Hardy I adenomas, 95.2% with Hardy II, 90.5% with Hardy III, and 47.4% with Hardy IV respectively. A significant postoperative improvement both in clinical symptoms and endocrinal parameters was achieved. The tumor recurrence rate was 0.3%.</p><p><b>CONCLUSIONS</b>With the improvement of microsurgical technique and application of novel technology, the indication of transsphenoidal microsurgery for pituitary adenomas was increasingly extended. Endoscope and(/or) neuronavigation-assisted microsurgery via transsphenoidal approach should be of the first choice for the treatment of pituitary adenomas. The routine postoperative radiotherapy is not required for patients with total tumor removal.</p>
Full text:
1
Index:
WPRIM
Main subject:
Pituitary Neoplasms
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Sphenoid Sinus
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General Surgery
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Adenoma
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Retrospective Studies
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Follow-Up Studies
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Treatment Outcome
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Neurosurgical Procedures
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Methods
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Microsurgery
Type of study:
Observational_studies
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Prognostic_studies
Limits:
Adolescent
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Adult
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Aged
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Aged80
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Child
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Female
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Humans
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Male
Language:
Zh
Journal:
Chinese Journal of Surgery
Year:
2003
Type:
Article